Radiotherapy

Automated treatment planning for a dedicated multi-source intra-cranial radiosurgery treatment unit accounting for overlapping structures and dose homogeneity
Purpose: The purpose of this work is to advance the two-step approach for Gamma Knife® Perfexion™ (PFX) optimization to account for …
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Computational enhancements to fluence map optimization for total marrow irradiation using IMRT
The fluence map optimization (FMO) problem is a core problem in intensity modulated radiation therapy (IMRT) treatment planning. …
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Incorporation of delivery times in Leksell Gamma Knife R Perfexion TM treatment optimization
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Optimization methods for large-scale radiotherapy problems
Optimization techniques are commonly applied to treatment design problems arising in radiation therapy. Previous literature on the …
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Optimization of dose schedules in radiotherapy
Purpose: Fractionation in radiotherapy is the scheduled break up of a total treatment dose into individual doses. The goal of this …
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A tractable mixed-integer model to design stereotactic radiosurgery treatments
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Automated treatment planning for a dedicated multi-source intracranial radiosurgery treatment unit using projected gradient and grassfire algorithms
Purpose: The purpose of this work is to develop a framework to the inverse problem for radiosurgery treatment planning on the Gamma …
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Optimization models and techniques for radiation treatment planning applied to Leksell Gamma Knife(R) Perfexion(TM)
Radiation treatment planning is a process through which a certain plan is devised in order to irradiate tumors or lesions to a …
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A set cover approach to fast beam orientation optimization in intensity modulated radiation therapy for total marrow irradiation
The beam orientation optimization (BOO) problem in intensity modulated radiation therapy (IMRT) treatment planning is a nonlinear …
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An interior point constraint generation algorithm for semi-infinite optimization with health-care application
We propose an interior point constraint generation (IPCG) algorithm for semi-infinite linear optimization (SILO) and prove that the …
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